Line S
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| Route Description | The S Line is a commuter route that connects the Palo Alto Transit Center with Stanford West, Oak Creek Apartments, SLAC, and the Rosewood Hotel. Bus stops are located at the Palo Alto Transit Center at Bus Depot Bay # 6, Quarry Rd, Stanford West, Sand Hill Rd, SLAC, and at the Rosewood Hotel. |
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| Frequency | AM S Line departures average every 45 minutes from Oak Creek Apartments. Service hours are 6:29 AM - 9:28 AM. PM S Line departures average every 44 minutes from Rosewood Hotel. Service hours are 4:13 PM - 6:25 PM. |
| Operation | The S Line operates on weekdays year-round excluding New Year's Day, Martin Luther King, Jr. Day, Presidents' Day, Memorial Day, Independence Day, Labor Day, Thanksgiving Day, Friday after Thanksgiving, Stanford winter closure, and Christmas. |